We develop solution formulations for every parenteral route of administration, including intravenous, subcutaneous and intramuscular. We go well beyond optimising for solubility only. Our formulations are designed to be well tolerated at the site of administration and to minimise the risk of precipitation after injection.
Excipients are selected within established safety limits to minimise haemolysis, irritation and side effects that could compromise your study.
Combined solubilisation
Co-solvents, cyclodextrins, surfactants and pH adjustment are combined where needed to reach your target concentration within tolerable excipient levels.
Precipitation risk assessed
Dilution after injection is simulated in detail in vitro, so your PK data is accurate and side effects are avoided.